Mouse Kallikrein 7/KLK7 Protein (active form) (KLK-MM107)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 90% as determined by Bis-Tris PAGE
  • Activity: Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2. The specific activity is >300 pmol/min/µg.
  • Amino Acid Range: Ile26-Arg249
Catalog #KLK-MM107
Regular price $375.00
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Mouse Kallikrein 7/KLK7 Protein (active form) (KLK-MM107) Summary

Product Description

Recombinant Mouse Kallikrein 7/KLK7 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Ile26-Arg249.

Product Background

Kallikrein 7 (KLK7) is a secreted serine protease with chymotrypsic protease activity. Abnormally high expression of KLK7 is closely related to the occurrence and development of various types of cancer. Therefore, KLK7 has been identified as a potential target for cancer drug development design in recent years. KLK7 mediates various biological and pathological processes in tumorigenesis, including cell proliferation, migration, invasion, angiogenesis, and cell metabolism, by hydrolyzing a series of substrates such as membrane proteins, extracellular matrix proteins, and cytokines.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Mouse Kallikrein 7/KLK7 Protein (active form) (KLK-MM107) Specifications/Details

Protein
Kallikrein 7/KLK7
Synonyms
Kallikrein-7; hK7; Serine protease 6; hSCCE; KLK7; PRSS6; SCCE
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Ile26-Arg249
Molecular Weight
The protein has a predicted MW of 26.21 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
Activity
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2. The specific activity is >300 pmol/min/µg.
Product Tag
C-His
Expression System
HEK293
Purity
> 90% as determined by Bis-Tris PAGE
Endotoxin
Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in 20mM NaAC, 150mM NaCl, 8% trehalose, 0.05% Brij-35, 5mM Benzamidine (pH 5.0).
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse Kallikrein 7 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. Mouse Kallikrein 7 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
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