Mouse KLRG1 Protein (KLR-MM2G1)
Mouse KLRG1 Protein (KLR-MM2G1)
Mouse KLRG1 Protein (KLR-MM2G1)
  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gln57-Tyr188
Catalog #KLR-MM2G1
Regular price $315.00
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Product Description

Recombinant Mouse KLRG1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln57-Tyr188.

Product Background

Immune homeostasis requires the tight, tissue-specific control of the different CD4 Foxp3 regulatory T (Treg) cell populations. The cadherin-binding inhibitory receptor killer cell lectin-like receptor G1 (KLRG1) is expressed by a subpopulation of Treg cells with GATA3 effector phenotype.Lack of KLRG1 on Treg cells conferred on them a competitive advantage in the gut, but not in lymphoid organs. Hence, although absence of KLRG1 is not enough to increase intestinal Treg cells in KLRG1 knockout mice, KLRG1 ligation reduces T-cell receptor signals and the competitive fitness of individual Treg cells in the intestine.

Product Category

Recombinant Protein / Antibody discovery

Protein

KLRG1

Synonyms

KLRG1; CLEC15A; MAFA; MAFAL; 2F1; CLEC15AMAFA-LIKE; MGC13600

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Gln57-Tyr188

Molecular Weight

The protein has a predicted MW of 42.3 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.

Product Tag

N-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse KLRG1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse KLRG1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse KLRG1 is greater than 95% as determined by SEC-HPLC. The purity of Mouse KLRG1 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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