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Mouse L1CAM Protein (LAM-MM101) Summary
Product Description |
Recombinant Mouse L1CAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile20-Glu1123. |
Product Background |
L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Mouse L1CAM Protein (LAM-MM101) Specifications/Details
Protein |
L1CAM |
Synonyms |
N-CAM-L1; NCAM-L1; CD171; L1CAM; CAML1; MIC5; CALL; CHL1; CHL-1; FLJ44930; L1CAM-2; MGC132578; HSAS; HSAS1; MASA; S10; SPG1 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ile20-Glu1123 |
Molecular Weight |
The protein has a predicted MW of 125.4 kDa. Due to glycosylation, the protein migrates to 160-180 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Mouse L1CAM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Mouse L1CAM is greater than 90% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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