Product Description |
Recombinant Mouse L1CAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile20-Glu1123. |
Product Background |
L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers. |
Product Category |
Recombinant Protein |
Target |
L1CAM |
Synonyms |
N-CAM-L1; NCAM-L1; CD171; L1CAM; CAML1; MIC5; CALL; CHL1; CHL-1; FLJ44930; L1CAM-2; MGC132578; HSAS; HSAS1; MASA; S10; SPG1 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ile20-Glu1123 |
Molecular Weight |
The protein has a predicted MW of 125.4 kDa. Due to glycosylation, the protein migrates to 160-180 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse L1CAM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse L1CAM is greater than 95% as determined by SEC-HPLC. |
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