Mouse LAIR1/CD305 Protein (LAI-MM1R1)
Mouse LAIR1/CD305 Protein (LAI-MM1R1)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gln22-Tyr141
Catalog #LAI-MM1R1
Regular price $223.30
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Product Description

Recombinant Mouse LAIR1/CD305 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln22-Tyr141.

Product Background

LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation.

Product Category

Recombinant Protein / Antibody discovery

Protein

LAIR1/CD305

Synonyms

CD305; HLAIR1; LAIR1; LAIR-1

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Gln22-Tyr141

Molecular Weight

The protein has a predicted MW of 14.6 kDa. Due to glycosylation, the protein migrates to 30-42 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse LAIR1 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. Mouse LAIR1 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of Mouse LAIR1 is greater than 95% as determined by SEC-HPLC. The purity of Mouse LAIR1 is greater than 95% as determined by SEC-HPLC.

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