• Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Asn25-Ser376
Catalog #GDF-MM108
Regular price $0.00
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Product Description

Recombinant Mouse Latent GDF-8 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Asn25-Ser376.

Product Background

Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain.

Product Category

Recombinant Protein / Antibody discovery

Protein

Latent GDF-8

Synonyms

Myostatin; GDF8; Latent GDF8; Mstn;

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Asn25-Ser376

Molecular Weight

The protein has a predicted MW of 42.2 kDa. Due to glycosylation, the protein migrates to 【】 kDa based on Bis-Tris PAGE result.

Product Tag

N-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 0.1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Mouse Latent GDF-8 is greater than 95% as determined by SEC-HPLC. The purity of Mouse Latent GDF-8 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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