Name: Mouse Latent GDF-8 Protein (GDF-MM128)
Brand: KactusBio
SKU: GDF-MM128-100UG
Price: 525.0 USD
Availability: InStock

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Mouse Latent GDF-8, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Apitegromab, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA.
Amino Acid Range: Asn25-Ser376
Recommended Products:
Loading...

Catalog #GDF-MM128

Size

100UG

500UG

Order by 4pm ET for delivery on:

Mouse Latent GDF-8 Protein (GDF-MM128) Summary

Product Description	Recombinant Mouse Latent GDF-8 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Asn25-Ser376.
Product Background	Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Mouse Latent GDF-8 Protein (GDF-MM128) Specifications/Details

Protein	GDF-8
Synonyms	Myostatin; GDF8; Latent GDF8; Mstn;
Accession	O08689
Species	Mouse
Biotinylated	no
Amino Acid Range	Asn25-Ser376
Molecular Weight	The protein has a predicted MW of 41.18 kDa. Due to glycosylation, the protein migrates to 14 kDa and 32-38 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Mouse Latent GDF-8, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Apitegromab, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA.
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Mouse Latent GDF-8, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Apitegromab, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA.
	Immobilized Mouse Latent GDF-8, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 25.1ng/ml determined by ELISA.
	Mouse Latent GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse Latent GDF-8 is greater than 90% as determined by SEC-HPLC.