Name: Mouse LGMN Protein (LGM-MM101)
Brand: KactusBio
SKU: LGM-MM101-100UG
Price: 264.0 USD
Availability: InStock

Catalog #LGM-MM101

Size

100UG

500UG

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Mouse LGMN Protein (LGM-MM101) Summary

Product Description	Recombinant Mouse LGMN Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Val18-Tyr435.
Product Background	Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in the pathogenesis of Alzheimer's disease (AD). In single-variant association analysis, none of the common variants in LGMN were statistically significant. In gene-based analysis, the LGMN gene also showed no association with AD.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Mouse LGMN Protein (LGM-MM101) Specifications/Details

Protein	LGMN
Synonyms	Legumain; Prsc1; AEP; LGMN; LGMN1; AI746452; AU022324
Accession	O89017
Species	Mouse
Biotinylated	no
Amino Acid Range	Val18-Tyr435
Molecular Weight	The protein has a predicted MW of 48.6 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Bis-Tris PAGE result.
Product Tag	N-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse LGMN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse LGMN is greater than 95% as determined by SEC-HPLC.

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