Mouse LGMN Protein (LGM-MM101)
Mouse LGMN Protein (LGM-MM101)
  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Val18-Tyr435
Catalog #LGM-MM101
Regular price $240.00
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Product Description

Recombinant Mouse LGMN Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Val18-Tyr435.

Product Background

Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in the pathogenesis of Alzheimer's disease (AD). In single-variant association analysis, none of the common variants in LGMN were statistically significant. In gene-based analysis, the LGMN gene also showed no association with AD.

Product Category

Recombinant Protein / Antibody discovery

Protein

LGMN

Synonyms

Legumain; Prsc1; AEP; LGMN; LGMN1; AI746452; AU022324

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Val18-Tyr435

Molecular Weight

The protein has a predicted MW of 48.6 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Bis-Tris PAGE result.

Product Tag

N-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse LGMN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse LGMN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse LGMN is greater than 95% as determined by SEC-HPLC. The purity of Mouse LGMN is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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