Name: Mouse LILRB4/CD85k/ILT3 Protein (LIL-MM1B4)
Brand: KactusBio
SKU: LIL-MM1B4-100UG
Price: 330.0 USD
Availability: InStock

Mouse LILRB4/CD85k/ILT3 Protein (LIL-MM1B4)

Mouse LILRB4, His Tag immobilized on CM5 Chip can bind Mouse APOE, His Tag with an affinity constant of 5.08 nM as determined in SPR assay (Biacore T200).

Mouse LILRB4 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

The purity of Mouse LILRB4 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 5.08 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gly24-Lys238

Catalog #LIL-MM1B4

Size

100UG

500UG

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Mouse LILRB4/CD85k/ILT3 Protein (LIL-MM1B4) Summary

Product Description	Recombinant Mouse LILRB4/CD85k/ILT3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly24-Lys238.
Product Background	LILRB4,also known as CD85k and LIR-5, ILT3,- is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Mouse LILRB4/CD85k/ILT3 Protein (LIL-MM1B4) Specifications/Details

Protein	LILRB4/CD85k/ILT3
Synonyms	HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Accession	Q64281-1
Species	Mouse
Biotinylated	no
Amino Acid Range	Gly24-Lys238
Molecular Weight	The protein has a predicted MW of 25.1 kDa. Due to glycosylation, the protein migrates to 30-45 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 5.08 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse LILRB4, His Tag immobilized on CM5 Chip can bind Mouse APOE, His Tag with an affinity constant of 5.08 nM as determined in SPR assay (Biacore T200).
	Mouse LILRB4 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
	The purity of Mouse LILRB4 is greater than 95% as determined by SEC-HPLC.