Name: Mouse LOX1 Protein (LOX-MM101)
Brand: KactusBio
SKU: LOX-MM101-100UG
Price: 270.0 USD
Availability: InStock

Catalog #LOX-MM101

Size

100UG

500UG

Order now, ships by:

Product Description	Recombinant Mouse LOX1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Arg60-Ile363.
Product Background	LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion also results in damage from ischemia, making LOX-1 a promising target of therapy for atherosclerosis and related disorders. In this article we focus on the different mechanisms for regulation, signaling and the various effects of LOX-1 in contributing to atherosclerosis.
Product Category	Recombinant Protein / Antibody discovery

Protein	LOX1
Synonyms	Ox-LDL receptor 1; LOX-1; CLEC8A; LOX1; OLR1; LOXIN; SR-E1; SCARE1; SLOX1
Accession	Q9EQ09
Species	Mouse
Biotinylated	no
Amino Acid Range	Arg60-Ile363
Molecular Weight	The protein has a predicted MW of 36.1 kDa. Due to glycosylation, the protein migrates to 55-63 kDa based on Bis-Tris PAGE result.
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse LOX1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse LOX1 is greater than 95% as determined by SEC-HPLC.