Mouse LTBR Protein (LTB-MM201)
Mouse LTBR Protein (LTB-MM201)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
  • Amino Acid Range: Gln31-Leu223
Catalog #LTB-MM201
Regular price $150.00
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Product Description
Recombinant Mouse LTBR Protein is expressed from HEK293 with hFc tag at the C-Terminus; It contains Gln31-Leu223.
Product Background
Components of lymphotoxin beta receptor (LTBR)-associated signaling complexes, including TRAF2, TRAF3, NIK, IKK1, and IKK2 have been shown to participate in the coupling of LTBR to NFkappaB. TRAF3 functions as a negative regulator of LTBR signaling via both canonical and non-canonical NFkappaB pathways by two distinct mechanisms. These effects of TRAF3 depletion did not require LTBR signaling and were consistent with autonomous activation of the non-canonical NFkappaB pathway.
Product Category
Recombinant Protein
Target
LTBR
Synonyms
TNFCR; TNFR3; TNFRSF3; LTBR; CD18; TNFR2-RP; TNFR-RP; LT-BETA-R; TNF-R-III; D12S370
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Gln31-Leu223
Molecular Weight
The protein has a predicted MW of 48.5 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Product Tag
C-hFc
Express System
HEK293
Purity
>95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse LTBR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse LTBR is greater than 95% as determined by SEC-HPLC.

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