Name: Mouse MASP2 Protein (MSP-ME102)
Brand: KactusBio
SKU: MSP-ME102-100UG
Price: 445.5 USD
Availability: InStock

Express System: E.coli
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Mouse MASP2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Narsoplimab, hFc Tag with the EC50 of 5.3ng/ml determined by ELISA.
Amino Acid Range: Thr287-Phe685

Catalog #MSP-ME102

Size

100UG

500UG

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Mouse MASP2 Protein (MSP-ME102) Summary

Product Description	Recombinant Mouse MASP2 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Thr287-Phe685.
Product Background	Te MASP2 gene is located on the chromosome 1p36.23–31 and encodes two proteins, MASP-2 and Map198. Both the levels and function of MASP-2 are modulated by the single-nucleotide polymorphisms (SNPs) of the MASP2 gene. Te level of MASP-2 in plasma plays a dual role in the infection and progression of infectious diseases. Te defciency of MASP-2 in plasma has been associated with the susceptibility of HIV. By contrast, the overproduction of MASP-2 may increase the infammatory efect.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Mouse MASP2 Protein (MSP-ME102) Specifications/Details

Protein	MASP2
Synonyms	MAP19; MASP-2; MASP1P1; sMap
Accession	Q91WP0
Species	Mouse
Biotinylated	no
Amino Acid Range	Thr287-Phe685
Molecular Weight	The protein has a predicted MW of 46.6 kDa. Due to autocatalytic cleavage, the protein migrates to 18-20 kDa&27-30 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Mouse MASP2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Narsoplimab, hFc Tag with the EC50 of 5.3ng/ml determined by ELISA.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 50mM Tris, 200mM NaCl (pH 9.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Mouse MASP2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Narsoplimab, hFc Tag with the EC50 of 5.3ng/ml determined by ELISA.
	Mouse MASP2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Narsoplimab on ProA-Biosensor can bind Mouse MASP2, His Tag with an affinity constant of 4.38 nM as determined in BLI assay .

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