Mouse MDL-1/CLEC5A Protein (CLE-MM25A)
Catalog: CLE-MM25A
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Product Description | Recombinant Mouse MDL-1/CLEC5A Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Tyr26-Lys190. |
Product Background |
In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality. |
Product Category |
Recombinant Protein |
Target |
MDL-1/CLEC5A |
Synonyms | MDL-1; CLECSF5; MDL1; CLEC5A; DAP12-associating lectin 1 |
Gene/Protein ID |
Q9R007-1 |
Species |
Mouse |
Exact Sequence |
Tyr26-Lys190 |
Molecular Weight | The protein has a predicted MW of 46.2 kDa. Due to glycosylation, the protein migrates to 64-68 kDa based on Tris-Bis PAGE result. |
Product Tag |
N-hFc |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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