SEC-HPLC chromatogram showing a single, sharp peak at approximately 6.9 minutes, indicating a highly pure and monomeric protein preparation.
Mouse MERTK/Mer Protein (MEK-MM101)
SEC-HPLC chromatogram showing a single, sharp peak at approximately 6.9 minutes, indicating a highly pure and monomeric protein preparation.
Mouse MERTK/Mer Protein (MEK-MM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly19-Met497
Catalog #MEK-MM101
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Size
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Mouse MERTK/Mer Protein (MEK-MM101) Summary

Product Description

 Recombinant Mouse MERTK/Mer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly19-Met497.

Product Background

 MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery | Others

Mouse MERTK/Mer Protein (MEK-MM101) Specifications/Details

Protein
 MERTK/Mer
Synonyms
 MERTK; MER; c-Eyk; MGC133349; c-mer; RP38; Tyro12
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Gly19-Met497
Molecular Weight
 The protein has a predicted MW of 53.38 kDa. Due to glycosylation, the protein migrates to 85-105 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse MERTK on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse MERTK on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse MERTK is greater than 95% as determined by SEC-HPLC. The purity of Mouse MERTK is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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