Name: Mouse MUC18/CD146 Protein (MUC-MM118)
Brand: KactusBio
SKU: MUC-MM118-100UG
Price: 315.0 USD
Availability: InStock

Catalog #MUC-MM118

Size

100UG

500UG

Order now, ships by:

Product Description	Recombinant Mouse MUC18/CD146 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val24-Val563.
Product Background	METCAM/MUC18 is an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family. It can carry out common functions of CAMs which is to perform intercellular interactions and interaction of cell with extracellular matrix in tumor microenvironment, to interact with various signaling pathways and to regulate general behaviors of cells.The above positive correlation is fortuitous; actually METCAM/MUC18 acts as a tumor and metastasis suppressor for the ovarian carcinoma cells.
Product Category	Recombinant Protein / Antibody discovery

Protein	MUC18/CD146
Synonyms	Gicerin; CD146; MCAM; MUC18
Accession	Q8R2Y2-1
Species	Mouse
Biotinylated	no
Amino Acid Range	Val24-Val563
Molecular Weight	The protein has a predicted MW of 60.9 kDa. Due to glycosylation, the protein migrates to 75-95 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse MUC18 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse MUC18 is greater than 95% as determined by SEC-HPLC.