Product Description |
Recombinant Mouse Notch 4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu1042-Leu1441. |
Product Background |
The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression correlates with Ki67. Notch-4 also plays a key role in breast cancer stem-like cells. |
Product Category |
Recombinant Protein |
Target |
Notch 4 |
Synonyms |
Notch4; Int-3; Int3; Notch-4; |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Glu1042-Leu1441 |
Molecular Weight |
The protein has a predicted MW of 42.91 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in PB, 500mM NaCl, 10% Glycerol (pH 7.0). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Mouse Notch 4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse Notch 4 is greater than 95% as determined by SEC-HPLC. |
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