Mouse NPR1/NPRA Protein (NPR-MM301)
  • Express System: HEK293
  • Product Tag: C-mFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Ser29-Glu469
Catalog #NPR-MM301
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Product Description
 Recombinant Mouse NPR1/NPRA Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus.It contains Ser29-Glu469.
Product Background
 NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation, presumably by a mechanism that is RGS2-dependent in the acute phase and RGS2-independent in the chronic phase.
Product Category
 Recombinant Protein
Target
 NPR1/NPRA
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Ser29-Glu469
Molecular Weight
 The protein has a predicted MW of 74.92 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Bis-Tris PAGE result.
Product Tag
 C-mFc
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse NPR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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