Mouse OSCAR Protein (OAR-MM201) Summary
Product Description |
Recombinant Mouse OSCAR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asp19-Asn228. |
Product Background |
Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and normal patients. OSCAR and tartrate-resistant acid phosphatase (TRAP) expression levels did not differ between the cartilage pannus junction (CPJ) and non-CPJ regions in active RA. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Mouse OSCAR Protein (OAR-MM201) Specifications/Details
Protein |
OSCAR |
Synonyms |
mOSCAR; OSCAR; PIGR3; PIgR-3; Poly-Ig receptor 3; MGC33613 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Asp19-Asn228 |
Molecular Weight |
The protein has a predicted MW of 49.7 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
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Mouse OSCAR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Mouse OSCAR is greater than 95% as determined by SEC-HPLC. |
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