Mouse Oncostatin M/OSM Protein (OSM-MM102)
Catalog: OSM-MM102
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| Product Description | Recombinant Mouse Oncostatin M/OSM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn25-Arg206. |
Product Background |
OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. |
Product Category |
Recombinant Protein |
Target |
Oncostatin M/OSM |
Gene/Protein ID |
P53347 |
Species |
Mouse |
Exact Sequence |
Asn25-Arg206 |
| Molecular Weight | The protein has a predicted MW of 21.64 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse Oncostatin M is greater than 95% as determined by SEC-HPLC. |
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Mouse Oncostatin M on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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