Product Description |
Recombinant Mouse P4HB Protein is expressed from HEK293 with His tag at the C-terminus.It contains Asp20-Leu509. |
Product Background |
Protein disulfide isomerase (PDI, also named P4HB) is a 57-kDa oxidoreductase that facilitates cysteine thiol reactions inside and outside the cell. It mediates reduction or oxidation of protein disulfide bonds, thiol/disulfide exchange reactions, and transfer of NO from one protein thiol to another. It also has chaperone properties. PDI is actively secreted by most, if not all, of the cell types involved in thrombosis, binds to integrins on the cell surface, and circulates as a soluble protein in blood. |
Product Category |
Recombinant Protein |
Target |
P4HB |
Synonyms |
PDI; ERp59; p55; Pdia1; Thbp |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Asp20-Leu509 |
Molecular Weight |
The protein has a predicted MW of 56.18 kDa. Due to glycosylation, the protein migrates to 57-70 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse P4HB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse P4HB is greater than 95% as determined by SEC-HPLC. |
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