Name: Mouse PD-L2/B7-DC Protein (PDL-MM102)
Brand: KactusBio
SKU: PDL-MM102-100UG
Price: 264.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Mouse PD-L2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human PD-1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA.
Amino Acid Range: Leu20-Trp221

Catalog #PDL-MM102

Size

100UG

500UG

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Mouse PD-L2/B7-DC Protein (PDL-MM102) Summary

Product Description	Recombinant Mouse PD-L2/B7-DC Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-Trp221.
Product Background	PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins \| ADC targets

Mouse PD-L2/B7-DC Protein (PDL-MM102) Specifications/Details

Protein	PD-L2/B7-DC
Synonyms	PDL2; PD-L2; Butyrophilin B7-DC; CD273, PDCD1 ligand 2; PDCD1L2; PDCD1LG2; B7DC; bA574F11.2; Btdc
Accession	Q9WUL5
Species	Mouse
Biotinylated	no
Amino Acid Range	Leu20-Trp221
Molecular Weight	The protein has a predicted MW of 23.92 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Mouse PD-L2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human PD-1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Mouse PD-L2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human PD-1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA.
	Mouse PD-L2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse PD-L2 is greater than 95% as determined by SEC-HPLC.