Name: Mouse PD-L2/B7-DC Protein (PDL-MM102)
Brand: KactusBio
SKU: PDL-MM102-100UG
Price: 240.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Mouse PD-L2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human PD-1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Leu20-Trp221

Catalog #PDL-MM102

Size

100UG

500UG

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Product Description	Recombinant Mouse PD-L2/B7-DC Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-Trp221.
Product Background	PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	PD-L2/B7-DC
Synonyms	PDL2; PD-L2; Butyrophilin B7-DC; CD273, PDCD1 ligand 2; PDCD1L2; PDCD1LG2; B7DC; bA574F11.2; Btdc
Accession	Q9WUL5
Species	Mouse
Biotinylated	no
Amino Acid Range	Leu20-Trp221
Molecular Weight	The protein has a predicted MW of 23.92 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Mouse PD-L2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human PD-1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Mouse PD-L2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human PD-1, hFc Tag with the EC50 of 0.32ug/ml determined by ELISA.
	Mouse PD-L2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse PD-L2 is greater than 95% as determined by SEC-HPLC.