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Mouse Pentraxin 2/SAP Protein (SAP-MM201) Summary
Product Description |
Recombinant Mouse Pentraxin 2/SAP Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gln21-Asp224. |
Product Background |
Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Mouse Pentraxin 2/SAP Protein (SAP-MM201) Specifications/Details
Protein |
Pentraxin 2/SAP |
Synonyms |
SAP; APCS; MGC88159; Pentraxin 2; PTX2 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Gln21-Asp224 |
Molecular Weight |
The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 90% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Mouse Pentraxin 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. |
|
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The purity of Mouse Pentraxin 2 is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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