Mouse PGF Protein (PGF-MM201)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Val19-Pro158

Catalog: PGF-MM201

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Product Description Recombinant Mouse PGF Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Val19-Pro158.

Product Background

Placental growth factor (PGF) is another member of the VEGF family of cytokines with pro-angiogenic and pro-inflammatory effects. Retinal inhibition of PGF in combination with VEGF-A prevents vascular leakage and CNV possibly via modulating their own expression in mononuclear phagocytes. PGF-related, optimized strategies to target inflammation-mediated angiogenesis may help to increase efficacy and reduce non-responders in the treatment of wet AMD patients.

Product Category

Recombinant Protein

Target

PGF
Synonyms PlGF; PGF; PGFL; SHGC-10760; D12S1900; PlGF-2

Gene/Protein ID

P49764

Species

Mouse

Exact Sequence

Val19-Pro158
Molecular Weight The protein has a predicted MW of 42.4 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse PGF is greater than 95% as determined by SEC-HPLC.
Mouse PGF on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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