Product Description |
Recombinant Mouse PGLYRP1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe19-Glu182. |
Product Background |
Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway. |
Product Category |
Recombinant Protein |
Target |
PGLYRP1 |
Synonyms |
PGRP-S; PGLYRP1; PGLYRP; PGRP; TNFSF3L; PGRP-SMGC126894; PGRPSMGC126896; TAG7; Tasg7 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Phe19-Glu182 |
Molecular Weight |
The protein has a predicted MW of 45.7 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in PBS, 10% Glycerol (pH 8.0). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Mouse PGLYRP1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse PGLYRP1 is greater than 95% as determined by SEC-HPLC. |
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