Mouse PRNP Protein (PRP-MM201)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Lys23-Ser230
Catalog #PRP-MM201
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Product Description
 Recombinant Mouse PRNP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys23-Ser230.
Product Background
 Prion protein gene (PRNP) variants determine the susceptibility of humans, sheep and mice to prion diseases, whereas polymorphisms in the open reading frame (ORF) of bovine PRNP seem to be unrelated to the incidence of bovine spongiform encephalopathy (BSE). According to the latest reports, the genetic susceptibility of cattle to BSE is associated with polymorphisms ofthe regulatory region of the PRNP gene and the level ofits expression.
Product Category
 Recombinant Protein
Target
 PRNP
Synonyms
 Major prion protein；PrP；ALTPRP；PRIP；PRP；PRNP
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Lys23-Ser230
Molecular Weight
 The protein has a predicted MW of 49.6 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Bis-Tris PAGE result.
Product Tag
 C-hFc
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse PRNP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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