Mouse PRNP Protein (PRP-MM201)
Catalog: PRP-MM201
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| Product Description | Recombinant Mouse PRNP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys23-Ser230. |
Product Background |
Prion protein gene (PRNP) variants determine the susceptibility of humans, sheep and mice to prion diseases, whereas polymorphisms in the open reading frame (ORF) of bovine PRNP seem to be unrelated to the incidence of bovine spongiform encephalopathy (BSE). According to the latest reports, the genetic susceptibility of cattle to BSE is associated with polymorphisms ofthe regulatory region of the PRNP gene and the level ofits expression. |
Product Category |
Recombinant Protein |
Target |
PRNP |
| Synonyms | Major prion protein；PrP；ALTPRP；PRIP；PRP；PRNP |
Gene/Protein ID |
P04925 |
Species |
Mouse |
Exact Sequence |
Lys23-Ser230 |
| Molecular Weight | The protein has a predicted MW of 49.6 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Mouse PRNP on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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