Mouse PSMP Protein (PSM-MM201)
Mouse PSMP Protein (PSM-MM201)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Lys37-Ser139
Catalog #PSM-MM201
Regular price $297.00
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Mouse PSMP Protein (PSM-MM201) Summary

Product Description

Recombinant Mouse PSMP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys37-Ser139.

Product Background

PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern molecules HMGB-1 and IL-33 induced hepatocytes to produce PSMP. PSMP promotes liver fibrosis through inflammatory macrophage infiltration, polarization and production of proinflammatory cytokines, as well as direct activation of hepatic stellate cells via its receptor CCR2.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Mouse PSMP Protein (PSM-MM201) Specifications/Details

Protein
PSMP
Synonyms
Msmp; Psmp; PC3-secreted microprotein
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Lys37-Ser139
Molecular Weight
The protein has a predicted MW of 37.9 kDa. Due to glycosylation, the protein migrates to 48-51 kDa based on Bis-Tris PAGE result.

Product Tag

C-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse PSMP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse PSMP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse PSMP is greater than 95% as determined by SEC-HPLC. The purity of Mouse PSMP is greater than 95% as determined by SEC-HPLC.
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