Mouse PVRIG Protein (PVR-MM501)
Mouse PVRIG Protein (PVR-MM501)
Mouse PVRIG Protein (PVR-MM501)
Mouse PVRIG Protein (PVR-MM501)
  • Express System: HEK293
  • Product Tag: C-hFc-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Mouse Nectin-2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Mouse PVRIG, hFc Tag with the EC50 of 0.62ug/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ser35-Asp165
Catalog #PVR-MM501
Regular price $315.00
/
Size

Order now, ships by:

Product Description

Recombinant Mouse PVRIG Protein is expressed from HEK293 with hFc tag and Avi tag at the C-Terminus.It contains Ser35-Asp165.

Product Background

Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein

PVRIG

Synonyms

C7orf15; CD112R; MGC104322; MGC138297; MGC2463; PVRIG; ALS2CR18; ALS2CR9; LPD; PREL-2; PREL2; RalGDS/AF-6; RMO1

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Ser35-Asp165

Molecular Weight

The protein has a predicted MW of 42.70 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Mouse Nectin-2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Mouse PVRIG, hFc Tag with the EC50 of 0.62ug/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-hFc-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Mouse Nectin-2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Mouse PVRIG, hFc Tag with the EC50 of 0.62ug/ml determined by ELISA (QC Test). Immobilized Mouse Nectin-2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Mouse PVRIG, hFc Tag with the EC50 of 0.62ug/ml determined by ELISA (QC Test).
Mouse PVRIG on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse PVRIG on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed