Mouse SEMA3A/Semaphorin-3A Protein (SEM-MM13A)
Mouse SEMA3A/Semaphorin-3A Protein (SEM-MM13A)
Mouse SEMA3A/Semaphorin-3A Protein (SEM-MM13A)
  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Tyr21-Val772
Catalog #SEM-MM13A
Regular price $330.00
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Product Description

Recombinant Mouse SEMA3A/Semaphorin-3A Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Tyr21-Val772.

Product Background

The CRMP proteins were originally identified as mediators of Sema3A signaling and neuronal differentiation. Much has been learned about the mechanism by which CRMPs regulate cellular responses to Sema3A.The secreted protein Sema3A (collapsin-1) was the first identified vertebrate semaphorin. Sema3A acts primarily as a repulsive axon guidance cue, and can cause a dramatic collapse of the growth cone lamellipodium.Neuropilin-1 (NP1) and members of the class A plexins (PlexA) form a Sema3A receptor complex, with NP1 serving as a high-affinity ligand binding partner, and PlexA transducing the signal into the cell via its large intracellular domain.

Product Category

Recombinant Protein / Antibody discovery

Protein

SEMA3A/Semaphorin-3A

Synonyms

Sema III; Semaphorin; Sema D; coll-1; collapsin 1; Hsema-I; Hsema-III; SEMA1, Sema3A; SEMAD; SEMAIII; SEMAL;Semaphorin 3A

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Tyr21-Val772

Molecular Weight

The protein has a predicted MW of 86.6 kDa. Due to furin cleavage site, the protein migrates to 65-70 kDa based on Bis-Tris PAGE result.

Product Tag

N-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 0.1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS, 200 mM L-Argine (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse SEMA3A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse SEMA3A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse SEMA3A is greater than 95% as determined by SEC-HPLC. The purity of Mouse SEMA3A is greater than 95% as determined by SEC-HPLC.

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