Mouse SEZ6 Protein (SEZ-MM106)
Mouse SEZ6 Protein (SEZ-MM106)
Mouse SEZ6 Protein (SEZ-MM106)
Mouse SEZ6 Protein (SEZ-MM106)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Activity: Immobilized Mouse SEZ6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Leu20-His922
Catalog #SEZ-MM106
Regular price $297.00
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Product Description

Recombinant Mouse SEZ6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-His922.

Product Background

Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
SEZ6
Synonyms
SEZ-6; SEZ6; BSRPC; BSRP-C
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Leu20-His922
Molecular Weight
The protein has a predicted MW of 98.8 kDa. Due to glycosylation, the protein migrates to 145-150 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Mouse SEZ6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Mouse SEZ6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA. Immobilized Mouse SEZ6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA.
Mouse SEZ6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse SEZ6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Loaded Anti-SEZ6 Antibody, hFc Tag on ProA-Biosensor can bind Mouse SEZ6, His Tag with an affinity constant of 0.21 µM as determined in BLI assay (Gator® Prime). Loaded Anti-SEZ6 Antibody, hFc Tag on ProA-Biosensor can bind Mouse SEZ6, His Tag with an affinity constant of 0.21 µM as determined in BLI assay (Gator® Prime).
The purity of Mouse SEZ6 is greater than 90% as determined by SEC-HPLC. The purity of Mouse SEZ6 is greater than 90% as determined by SEC-HPLC.
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