Name: Mouse Siglec-5/CD170 Protein (SIG-MM105)
Brand: KactusBio
SKU: SIG-MM105-100UG
Price: 315.0 USD
Availability: InStock

Catalog #SIG-MM105

Size

100UG

500UG

Order now, ships by:

Product Description	Recombinant Mouse Siglec-5/CD170 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr17-Leu439.
Product Background	Interactions between endothelial selectins and the leukocyte counter-receptor PSGL1 mediates leukocyte recruitment to inflammation sites. PSGL1 is highly sialylated, making it a potential ligand for Siglec-5, a leukocyte-receptor that recognizes sialic acid structures. Binding assays using soluble Siglec-5 variants (sSiglec-5/C4BP and sSiglec-5/Fc) revealed a dose- and calcium-dependent binding to PSGL1.
Product Category	Recombinant Protein / Antibody discovery

Protein	Siglec-5/CD170
Synonyms	CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2
Accession	Q920G3
Species	Mouse
Biotinylated	no
Amino Acid Range	Thr17-Leu439
Molecular Weight	The protein has a predicted MW of 46.8 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse Siglec-5/CD170 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse Siglec-5/CD170 is greater than 95% as determined by SEC-HPLC.