Mouse Siglec-5/CD170 Protein (SIG-MM105)
Mouse Siglec-5/CD170 Protein (SIG-MM105)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Thr17-Leu439
Catalog #SIG-MM105
Regular price $315.00
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Product Description

Recombinant Mouse Siglec-5/CD170 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr17-Leu439.

Product Background

Interactions between endothelial selectins and the leukocyte counter-receptor PSGL1 mediates leukocyte recruitment to inflammation sites. PSGL1 is highly sialylated, making it a potential ligand for Siglec-5, a leukocyte-receptor that recognizes sialic acid structures. Binding assays using soluble Siglec-5 variants (sSiglec-5/C4BP and sSiglec-5/Fc) revealed a dose- and calcium-dependent binding to PSGL1.

Product Category

Recombinant Protein / Antibody discovery

Protein

Siglec-5/CD170

Synonyms

CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Thr17-Leu439

Molecular Weight

The protein has a predicted MW of 46.8 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse Siglec-5/CD170 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse Siglec-5/CD170 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse Siglec-5/CD170 is greater than 95% as determined by SEC-HPLC. The purity of Mouse Siglec-5/CD170 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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