Mouse Siglec-5/CD170 Protein (SIG-MM105)
Mouse Siglec-5/CD170 Protein (SIG-MM105)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Thr17-Leu439
Catalog #SIG-MM105
Regular price $315.00
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Product Description
Recombinant Mouse Siglec-5/CD170 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr17-Leu439.
Product Background
Interactions between endothelial selectins and the leukocyte counter-receptor PSGL1 mediates leukocyte recruitment to inflammation sites. PSGL1 is highly sialylated, making it a potential ligand for Siglec-5, a leukocyte-receptor that recognizes sialic acid structures. Binding assays using soluble Siglec-5 variants (sSiglec-5/C4BP and sSiglec-5/Fc) revealed a dose- and calcium-dependent binding to PSGL1.
Product Category
Recombinant Protein
Target
Siglec-5/CD170
Synonyms
CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Thr17-Leu439
Molecular Weight
The protein has a predicted MW of 46.8 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse Siglec-5/CD170 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse Siglec-5/CD170 is greater than 95% as determined by SEC-HPLC.

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