Mouse SOST/Sclerostin Protein (SOT-MM101)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Amino Acid Range: Gln24-Tyr211

Catalog: SOT-MM101

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Product Description Recombinant Mouse SOST/Sclerostin Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln24-Tyr211.

Product Background

SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Product Category

Recombinant Protein

Target

SOST/Sclerostin
Synonyms sclerostin; SOST; VBCHsclerosteosis; CDD; DAND6; SOST1; VBCH
Accession

Species

Mouse

Amino Acid Range

Gln24-Tyr211
Molecular Weight The protein has a predicted MW of 22 kDa. Due to glycosylation,the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.

Product Tag

N-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse SOST on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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