Name: Mouse SOST/Sclerostin Protein (SOT-MM101)
Brand: KactusBio
SKU: SOT-MM101-100UG
Price: 240.0 USD
Availability: InStock

Mouse SOST/Sclerostin Protein (SOT-MM101)

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Mouse SOST, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 15.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gln24-Tyr211

Catalog #SOT-MM101

Size

100UG

500UG

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Product Description	Recombinant Mouse SOST/Sclerostin Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln24-Tyr211.
Product Background	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Product Category	Recombinant Protein

Target	SOST/Sclerostin
Synonyms	sclerostin; SOST; VBCHsclerosteosis; CDD; DAND6; SOST1; VBCH
Accession	Q99P68
Species	Mouse
Biotinylated	no
Amino Acid Range	Gln24-Tyr211
Molecular Weight	The protein has a predicted MW of 22 kDa. Due to glycosylation,the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Mouse SOST, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 15.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	N-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Mouse SOST, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 15.0ng/ml determined by ELISA (QC Test).
	Mouse SOST on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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