Mouse TFPI-2 Protein (TFP-MM102)
Catalog: TFP-MM102
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| Product Description | Recombinant Mouse TFPI-2 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu23-Ser230. |
Product Background |
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Moreover, in sputum from cystic fibrosis patients TFPI-2 C-terminal fragments are generated and found associated with immunoglobulins. Together our data describe a previously unknown host defense mechanism and therapeutic importance of TFPI-2 against invading Gram-negative bacterial pathogens. |
Product Category |
Recombinant Protein |
Target |
TFPI-2 |
| Accession | |
Species |
Mouse |
Amino Acid Range |
Leu23-Ser230 |
| Molecular Weight | The protein has a predicted MW of 24.87 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Mouse TFPI-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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