Mouse TIMP-2 Protein (TIM-MM1P2)
Catalog: TIM-MM1P2
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| Product Description | Recombinant Mouse TIMP-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys27-Pro220. |
Product Background |
Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs).TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes. TIMP-2 also has erythroid‑potentiating and cell growth promoting activities. |
Product Category |
Recombinant Protein |
Target |
TIMP-2 |
| Synonyms | CSC-21K; TIMP2; DDC8; TIMP-2 |
Gene/Protein ID |
P25785 |
Species |
Mouse |
Exact Sequence |
Cys27-Pro220 |
| Molecular Weight | The protein has a predicted MW of 22.8 kDa. Due to glycosylation, the protein migrates to 24-26 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse TIMP-2 is greater than 95% as determined by SEC-HPLC. |
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Mouse TIMP-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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