• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Val23-Gly258
Catalog #TNF-MM1R2
Price
Regular price $27000
Regular price Sale price $27000
/
Size
Avantor VWR Fisher Scientific

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Mouse TNFR2/CD120b/TNFRSF1B Protein (TNF-MM1R2) Summary

Product Description

 Recombinant Mouse TNFR2/CD120b/TNFRSF1B Protein is expressed from HEK293 with His tag at the C-terminus.It contains Val23-Gly258.

Product Background

 Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Mouse TNFR2/CD120b/TNFRSF1B Protein (TNF-MM1R2) Specifications/Details

Protein
 TNFR2/CD120b/TNFRSF1B
Synonyms
 CD120b; Etanercept; p75TBPII; p75TNFR; TNF RII; TNF-R2; TNF-R75; TNFR80; TNFRSF1B; TNFR2; TBPII; TNFBR; TNFR1B
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Val23-Gly258
Molecular Weight
 The protein has a predicted MW of 26.94 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse TNFR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse TNFR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse TNFR2 is greater than 95% as determined by SEC-HPLC. The purity of Mouse TNFR2 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...