Product Description |
Recombinant Mouse TNFSF15 Protein is expressed from HEK293 with monomeric Fc tag at the N-terminus.It contains Ala61-Leu252. |
Product Background |
TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or colitis and actively participate in the immunological pathways that underlie mucosal homeostasis and intestinal inflammation.Recently, an important role was demonstrated for TL1A/DR3 as potential mediators of intestinal fibrosis that is associated with the presence of gut inflammation. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
TNFSF15 |
Synonyms |
TL1A; VEGI-251; TNFSF15; TL1; VEGI; VEGI192A |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ala61-Leu252 |
Molecular Weight |
The protein has a predicted MW of 45.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Mouse DR3, His Tag at 0.5ug/ml(100ul/well) on the plate. Dose response curve for Mouse TNFSF15, monomeric Fc Tag with the EC50 of 2.3ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
N-monomeric Fc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Immobilized Mouse DR3, His Tag at 0.5ug/ml(100ul/well) on the plate. Dose response curve for Mouse TNFSF15, monomeric Fc Tag with the EC50 of 2.3ng/ml determined by ELISA (QC Test). |
|
|
Mouse TNFSF15 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse TNFSF15 is greater than 95% as determined by SEC-HPLC. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
More from Antibody Drug Discovery Proteins
Recently viewed
