Name: Mouse Thyroid Peroxidase Protein (TPO-MM101)
Brand: KactusBio
SKU: TPO-MM101-100UG
Price: 300.0 USD
Availability: InStock

Mouse Thyroid Peroxidase Protein (TPO-MM101)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gly32-Arg834

Catalog #TPO-MM101

Size

100UG

500UG

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Product Description	Recombinant Mouse Thyroid Peroxidase Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly32-Arg834.
Product Background	Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormone synthesis by catalyzing both the iodination of tyrosine residues to form monoiodotyrosine (MIT) and diiodotyrosine (DIT) residues and the coupling of iodotyrosine residues in Tg, resulting in the formation of T3 and T4. It is a frequent epitope of autoantibodies in autoimmune thyroid disease, for example, the expression of thyroid peroxidase is lost in papillary thyroid carcinoma.
Product Category	Recombinant Protein

Target	Thyroid Peroxidase
Synonyms	TPO; THPO; MGC163194; MGDF; MKCSF; ML; MPLLG; THCYT1; MGDFC-mpl ligand; MK-CSF; MPL ligand; Thrombopoietin; TPOMKCSF
Accession	P35419
Species	Mouse
Biotinylated	no
Amino Acid Range	Gly32-Arg834
Molecular Weight	The protein has a predicted MW of 90.6 kDa. Due to glycosylation, the protein migrates to 100-115 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Mouse Thyroid Peroxidase on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse Thyroid Peroxidase is greater than 95% as determined by SEC-HPLC.

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