Name: Mouse VEGF R3/FLT4 Protein (VGF-MM2R3)
Brand: KactusBio
SKU: VGF-MM2R3-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Mouse VEGF R3, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF-C, His Tag with the EC50 of 10.0ng/ml determined by ELISA (QC Test). The affinity constant of 12.93 pM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Tyr25-Glu775

Catalog #VGF-MM2R3

Size

100UG

500UG

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Product Description	Recombinant Mouse VEGF R3/FLT4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Tyr25-Glu775.
Product Background	Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Protein	VEGF R3/FLT4
Synonyms	VEGFR-3; FLT-4; LMPH1A; PCLFLT41; VEGFR3; FLT-41; PCL
Accession	P35917
Species	Mouse
Biotinylated	no
Amino Acid Range	Tyr25-Glu775
Molecular Weight	The protein has a predicted MW of 111.69 kDa. Due to glycosylation, the protein migrates to 115-160 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Mouse VEGF R3, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF-C, His Tag with the EC50 of 10.0ng/ml determined by ELISA (QC Test). The affinity constant of 12.93 pM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse VEGF R3, hFc Tag captured on CM5 Chip via Protein A can bind Human VEGF-C, His Tag with an affinity constant of 12.93 pM as determined in SPR assay (Biacore T200).
	Immobilized Mouse VEGF R3, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human VEGF-C, His Tag with the EC50 of 10.0ng/ml determined by ELISA (QC Test).
	Mouse VEGF R3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse VEGF R3 is greater than 95% as determined by SEC-HPLC.