Product Description |
Recombinant Mouse VNN1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu24-Asn488. |
Product Background |
Vanin-1 (VNN1) is anchored to the cellular membrane with pantetheinase activity, which hydrolyzes pantetheine to produce cysteamine. VNN1 can promote oxidative stress and the inflammatory response. Additionally, VNN1 has been confirmed to be overexpressed in cancer tissues of patients with PCAD and can be used as a blood biomarker for the discrimination of PCAD from type 2 diabetes. |
Product Category |
Recombinant Protein |
Target |
VNN1 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Leu24-Asn488 |
Molecular Weight |
The protein has a predicted MW of 53.14 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4. Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse VNN1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse VNN1 is greater than 95% as determined by SEC-HPLC. |
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