Murine RNase Inhibitor, GMP Grade (GMP-RNI-ME101)

  • Quality Statement:
    Manufactured to the GMP guidelines

    Antibiotic-free and animal-free production

    Suitable for manufacturing of mRNA therapeutics and vaccines
  • Express System: E.coli

Catalog: GMP-RNI-ME101

$650.00
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Product Description RNase inhibitors are essential to protect RNA from RNase contamination. It inhibits the enzymatic activity of RNases by noncovalently binding to the active site. Murine RNase inhibitor is a recombinant RNase inhibitor of murine origin expressed and purified in E.coli. It specifically inactivates RNases such as RNaseA, RNaseB, and C by binding covalently with RNase to form a 1:1 complex. Murine RNase Inhibitor is compatible with RNA synthesis, RT-PCR and other RNA-related reactions.
Expressed in an E.coli strain with the RNase inhibitor gene from mouse.
Product Category GMP Enzyme
Application In Vitro Transcription
RT-PCR
cDNA synthesis
Concentration 40 U/UL
Unit Definition One unit is defined as the amount of Murine RNase Inhibitor required to inhibit the activity of 5ng of RNase A by 50%. Activity is measured by the inhibition of hydrolysis of cytidine 2', 3'-cyclic monophosphate by RNase A.
Molecular Weight 50 kD
Express System E.coli
Quality Statement
Manufactured to the GMP guidelines

Antibiotic-free and animal-free production

Suitable for manufacturing of mRNA therapeutics and vaccines
QC Standard Activity: >=40 kU/ml
Purity: >=95%
Residual Endonuclease: Negative
Residual Exonuclease: Negative
Residual RNase: Negative
Residual Protease: Negative
Endotoxin: <=10 EU/ml
Residual Host Cell DNA: <=100 pg/MG
Residual Host Protein: <=50 ng/MG
Bioburden: <=1 CFU/10 ml
Form Liquid
Shipping Shipped with blue ice
Stability And Storage -20°C for 12 months. Avoid repeated freeze-thaw cycles.

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