PE-Labeled Cynomolgus HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-CM41CTP) Summary
Product Description |
Recombinant PE-Labeled Cynomolgus HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, PE-Labeled Cynomolgus HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide. |
Product Background |
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition. |
HLA-G&B2M&Peptide (RIIPRHLQL) Specifications
Protein |
HLA-G&B2M&Peptide (RIIPRHLQL) |
Synonyms |
HLA G antigen; sHLA-G; b2 microglobulin; HLA G; HLAG; HLA-G; MHC Class I Antigen G; MHC class Ib antigen; MHC-G; sHLA-G |
MHC Form |
Tetramer |
Allele |
HLA-G |
Accession |
E0WKX9(HLA-G)&Q8SPW0(B2M)&RIIPRHLQL |
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide |
Product Tag |
C-His-Avi |
Fluorophore |
PE-Labeled |
Expression System |
HEK293 |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 100mM L-Arginine, 0.2%BSA (pH 7.4). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins: