• Express System: HEK293
  • Product Tag: C-His-Avi
  • Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide
Catalog #MHC-HM459TP
Price
Regular price $1,26500
Regular price Sale price $1,26500
/
Size
Avantor VWR Fisher Scientific

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PE-Labeled Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein (MHC-HM459TP) Summary

Product Description

 Recombinant PE-Labeled Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer is assembled by biotinylated monomer and PE-Labeled streptavidin.It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and GLYDGMEHL peptide.

Product Background

 MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells.

HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Specifications

Protein
 HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL)
Synonyms
 MAGE-A10
MHC Form
 Tetramer
Allele
 HLA-A*02:01
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide
Product Tag
 C-His-Avi
Fluorophore
 PE-Labeled
Expression System
 HEK293

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS, 0.2% BSA (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Additional Information
Learn More: MHC Collection Learn More: Peptide-ready MHC Protocol: MHC Staining Case Study: Peptide-ready MHC for TCR Staining Poster: Engineering MHCs as Versatile Reagents Publication: Use of our Peptide-Ready MHCs in CAR-T Cell Research Product Brochure
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