Name: PE-Labeled Human HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Tetramer Protein (MHC-HE450TP)
Brand: KactusBio
SKU: MHC-HE450TP-100UG
Price: 1050.0 USD
Availability: InStock

Express System: E.coli
Product Tag: C-His-Avi
Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and CLAVEEVSL peptide

Catalog #MHC-HE450TP

Size

100UG

500UG

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PE-Labeled Human HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Tetramer Protein (MHC-HE450TP) Summary

Product Description	Recombinant PE-Labeled Human HLA-A02:01&B2M&NPM1-CLAV (CLAVEEVSL) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A02:01&B2M&NPM1-CLAV (CLAVEEVSL) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and CLAVEEVSL peptide.
Product Background	The nucleophosmin (NPM1) mutant protein, a-leukemia-associated antigen-characterized by its leukemia-restricted expression and immunogenic potential, has emerged as a promising therapeutic target for acute myeloid leukemia (AML) immunotherapy. Among its immunogenic epitopes, the-CLAVEEVSL peptide-derived from the full C-terminal region of the NPM1-mutated isoform demonstrates potent immunogenicity, making it a prime candidate for T cell-based immunotherapies.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Specifications

Protein	HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL)
Synonyms	NPM1-CLAV (CLAVEEVSL); NPM1-CLAV; CLAVEEVSL;
MHC Form	Tetramer
Allele	HLA-A*02:01
Accession	A0A140T913(HLA-A*02:01)&P61769(B2M)&CLAVEEVSL
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and CLAVEEVSL peptide
Product Tag	C-His-Avi
Fluorophore	PE-Labeled
Expression System	E.coli

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 20mM Tris, 200mM NaCl, 0.2% BSA (pH 8.0).
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Other Available Proteins:

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PE-Labeled Human HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Tetramer Protein (MHC-HE450TP) Summary

Product Description

Product Background

Product Category

HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Specifications

MHC Form

Allele

Fluorophore

Shipping, Reconstitution, & Storage

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