• Express System: HEK293
  • Product Tag: C-His-Avi
  • Amino Acid Range: Gly25-Thr305(HLA-A*02:03), Ile21-Met119(B2M) and FMNKFIYEI peptide
Catalog #MHC-HM432TP
Regular price $1,265.00
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PE-Labeled Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein (MHC-HM432TP) Summary

Product Description

Recombinant PE-Labeled Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-A*02:03), Ile21-Met119(B2M) and FMNKFIYEI peptide.

Product Background

Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.

Product Category

Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Specifications

Protein
HLA-A*02:03&B2M&AFP (FMNKFIYEI)
Synonyms
Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-feto; AFP; HPAFP; AFPD; FETA; MHC

MHC Form

Tetramer

Allele

HLA-A*02:03
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gly25-Thr305(HLA-A*02:03), Ile21-Met119(B2M) and FMNKFIYEI peptide

Product Tag

C-His-Avi

Fluorophore

PE
Expression System
HEK293
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in PBS, 0.2% BSA (pH 7.4).
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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