Name: PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein (MHC-HE039TP)
Brand: KactusBio
SKU: MHC-HE039TP-100UG
Price: 1150.0 USD
Availability: InStock

PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein (MHC-HE039TP)

Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA.

Express System: E.coli
Product Tag: C-His-Avi
Activity: Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide

Catalog #MHC-HE039TP

Size

100UG

500UG

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Product Description	Recombinant PE-Labeled Human HLA-A11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide.
Product Background	The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.
Product Category	Recombinant Protein / Antibody discovery / MHC

Protein	HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer
Synonyms	ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2
MHC Form	Tetramer
Allele	HLA-A*11:01
Accession	AAV53343.1(HLA-A*11:01)&P61769(B2M)&KITDFGRAK
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide
Activity	Immobilized PE-Labeled Human HLA-A11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Fluorophore	PE
Expression System	E.coli
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 0.2% BSA (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA.

Additional Information

Learn More: MHC Collection Learn More: Peptide-ready MHC Protocol: MHC Staining Case Study: Peptide-ready MHC for TCR Staining Poster: Engineering MHCs as Versatile Reagents Publication: Use of our Peptide-Ready MHCs in CAR-T Cell Research Product Brochure