Name: PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein (MHC-HE039TP)
Brand: KactusBio
SKU: MHC-HE039TP-100UG
Price: 1265.0 USD
Availability: InStock

PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein (MHC-HE039TP)

Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA.

Express System: E.coli
Product Tag: C-His-Avi
Activity: Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide

Catalog #MHC-HE039TP

Size

100UG

500UG

Order now, ships by:

[{"id":46279007437022,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"MHC-HE039TP-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"PE-Labeled Human HLA-A*11:01\u0026B2M\u0026EGFR L858R (KITDFGRAK) Tetramer Protein (MHC-HE039TP) - 100UG","public_title":"100UG","options":["100UG"],"price":126500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":46279191298270,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"MHC-HE039TP-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"PE-Labeled Human HLA-A*11:01\u0026B2M\u0026EGFR L858R (KITDFGRAK) Tetramer Protein (MHC-HE039TP) - 500UG","public_title":"500UG","options":["500UG"],"price":467500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant PE-Labeled Human HLA-A11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide.
Product Background	The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

Protein	HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK)
Synonyms	ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2
MHC Form	Tetramer
Allele	HLA-A*11:01
Accession	AAV53343.1(HLA-A*11:01)&P61769(B2M)&KITDFGRAK
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide
Activity	Immobilized PE-Labeled Human HLA-A11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Fluorophore	PE
Expression System	E.coli
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 0.2% BSA (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA.

Additional Information

Learn More: MHC Collection Learn More: Peptide-ready MHC Protocol: MHC Staining Case Study: Peptide-ready MHC for TCR Staining Poster: Engineering MHCs as Versatile Reagents Publication: Use of our Peptide-Ready MHCs in CAR-T Cell Research Product Brochure