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PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein (MHC-HE039TP) Summary
Product Description |
Recombinant PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide. |
Product Background |
The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. |
Product Category |
Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs, ADC targets |
HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Specifications
Protein |
HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) |
Synonyms |
ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2 |
MHC Form |
Tetramer |
Allele |
HLA-A*11:01 |
Accession |
AAV53343.1(HLA-A*11:01)&P61769(B2M)&KITDFGRAK |
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide |
Activity |
Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. |
Product Tag |
C-His-Avi |
Fluorophore |
PE-Labeled |
Expression System |
E.coli |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 0.2% BSA (pH 7.4). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. |
Additional Information
Other Available Proteins:
Finding available proteins...
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