• Express System: E.coli
  • Product Tag: C-His-Avi
  • Activity: Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA.
  • Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide
Catalog #MHC-HE039TP
Price
Regular price $1,05000
Regular price Sale price $1,05000
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Size
Avantor VWR Fisher Scientific

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PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein (MHC-HE039TP) Summary

Product Description

 Recombinant PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide.

Product Background

 The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.

HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Specifications

Protein
 HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK)
Synonyms
 ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2;EC2.7.10; EC2.7.10.1
MHC Form
 Tetramer
Allele
 HLA-A*11:01
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGRAK peptide
Activity
 Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA.
Product Tag
 C-His-Avi
Fluorophore
 PE-Labeled
Expression System
 E.coli

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS, 0.2% BSA (pH 7.4).
Stability And Storage
 Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. Immobilized PE-Labeled Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA.
Additional Information
Learn More: MHC Collection Learn More: Peptide-ready MHC Protocol: MHC Staining Case Study: Peptide-ready MHC for TCR Staining Poster: Engineering MHCs as Versatile Reagents Publication: Use of our Peptide-Ready MHCs in CAR-T Cell Research Product Brochure
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