PE-Labeled Human HLA-A*11:01&B2M&PRAME (AAFDGRHSQTLK) Tetramer Protein (MHC-HE474TP) Summary
Product Description |
Recombinant PE-Labeled Human HLA-A*11:01&B2M&PRAME (AAFDGRHSQTLK) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A*11:01&B2M&PRAME (AAFDGRHSQTLK) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and AAFDGRHSQTLK peptide. |
Product Background |
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited. |
HLA-A*11:01&B2M&PRAME (AAFDGRHSQTLK) Specifications
Protein |
HLA-A*11:01&B2M&PRAME (AAFDGRHSQTLK) |
Synonyms |
PRAME; OIP-4; OIP4; MAPE; |
MHC Form |
Tetramer |
Allele |
HLA-A*11:01 |
Accession |
AAV53343.1(HLA-A*11:01)&P61769(B2M)&AAFDGRHSQTLK |
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and AAFDGRHSQTLK peptide |
Product Tag |
C-His-Avi |
Fluorophore |
PE-Labeled |
Expression System |
E.coli |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 20mM Tris, 200mM NaCl, 0.2%BSA (pH 8.0). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins: