PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM41CTP)
PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM41CTP)
PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM41CTP)
PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM41CTP)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Activity: Immobilized PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA.
  • Amino Acid Range: Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide
  • Other Available Proteins:
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Catalog #HLG-HM41CTP
Regular price $1,050.00
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PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM41CTP) Summary

Product Description

Recombinant PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305 (HLA-G), Ile21-Met119 (B2M) and RIIPRHLQL peptide.

Product Background

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.

Product Category

Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-G&B2M&Peptide (RIIPRHLQL) Specifications

Protein
HLA-G&B2M&Peptide (RIIPRHLQL)
Synonyms
HLA G antigen; sHLA-G; b2 microglobulin; HLA G; HLAG; HLA-G; MHC Class I Antigen G; MHC class Ib antigen; MHC-G; sHLA-G

MHC Form

Tetramer

Allele

HLA-G
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide
Activity
Immobilized PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA.
Product Tag
C-His-Avi

Fluorophore

PE-Labeled
Expression System
HEK293

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in PBS, 0.2% BSA (pH 7.4).
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA. Immobilized PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA.
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