PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM41CTP)

Immobilized PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA.

Express System: HEK293
Product Tag: C-His-Avi
Activity: Immobilized PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide

Catalog #HLG-HM41CTP

Size

100UG

500UG

Order now, ships by:

[{"id":42885105778910,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"HLG-HM41CTP-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"PE-Labeled Human HLA-G\u0026B2M\u0026Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM41CTP) - 100UG","public_title":"100UG","options":["100UG"],"price":126500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584158105822,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"HLG-HM41CTP-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"PE-Labeled Human HLA-G\u0026B2M\u0026Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM41CTP) - 500UG","public_title":"500UG","options":["500UG"],"price":467500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305 (HLA-G), Ile21-Met119 (B2M) and RIIPRHLQL peptide.
Product Background	HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
Product Category	Recombinant Protein / Antibody discovery / MHC

Protein	HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer
Synonyms	HLA G antigen; sHLA-G; b2 microglobulin; HLA G; HLAG; HLA-G; MHC Class I Antigen G; MHC class Ib antigen; MHC-G; sHLA-G
MHC Form	Tetramer
Allele	HLA-G
Accession	P17693-1(HLA-G)&P61769(B2M)&RIIPRHLQL
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide
Activity	Immobilized PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Fluorophore	PE
Expression System	HEK293
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in PBS, 0.2% BSA (pH 7.4).
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Immobilized PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA.

Additional Information

Learn More: MHC Collection Learn More: Peptide-ready MHC Protocol: MHC Staining Case Study: Peptide-ready MHC for TCR Staining Poster: Engineering MHCs as Versatile Reagents Publication: Use of our Peptide-Ready MHCs in CAR-T Cell Research Product Brochure