PE-Labeled Human HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein (MHC-HM438TP)

  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Exact Sequence: Gly25-Thr305(HLA-C 03:04), Ile21-Met119(B2M) and GADGVGKSAL peptide

Catalog: MHC-HM438TP

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Product Description Recombinant PE-Labeled Human HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, PE-Labeled Human HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-C 03:04), Ile21-Met119(B2M) and GADGVGKSAL peptide.

Product Background

Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

Product Category

Recombinant Protein

Target

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer
MHC Form Tetramer
Allele HLA-C 03:04

Gene/Protein ID

QAV56463.1(HLA-C*03:04)&P61769(B2M)&GADGVGKSAL

Species

Human

Exact Sequence

Gly25-Thr305(HLA-C 03:04), Ile21-Met119(B2M) and GADGVGKSAL peptide

Product Tag

C-His-Avi

Fluorophore

PE

Express System

HEK293
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in PBS, 0.2% BSA (pH 7.4).
Stability And Storage Valid for 6 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

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