• Express System: HEK293
  • Product Tag: C-His-Avi
  • Amino Acid Range: Gly25-Thr305(HLA-C 03:04), Ile21-Met119(B2M) and GADGVGKSAL peptide
Catalog #MHC-HM438TP
Regular price $1,150.00
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Product Description
Recombinant PE-Labeled Human HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, PE-Labeled Human HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-C 03:04), Ile21-Met119(B2M) and GADGVGKSAL peptide.
Product Background
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Product Category
Recombinant Protein
Target
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer
MHC Form
Tetramer
Allele
HLA-C 03:04
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gly25-Thr305(HLA-C 03:04), Ile21-Met119(B2M) and GADGVGKSAL peptide
Product Tag
C-His-Avi
Fluorophore
PE
Express System
HEK293
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in PBS, 0.2% BSA (pH 7.4).
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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