Name: PE-Labeled Mouse H-2K(b)&B2M&OVA (SIINFEKL) Tetramer Protein (MHC-MM453TP)
Brand: KactusBio
SKU: MHC-MM453TP-100UG
Price: 1265.0 USD
Availability: InStock

PE-Labeled Mouse H-2K(b)&B2M&OVA (SIINFEKL) Tetramer Protein (MHC-MM453TP)

PE-Labeled Mouse H-2K(b)&B2M&OVA (SIINFEKL) Tetramer can specifically bind to CD8+, OVA-specific T cells from OT-I TCR transgenic mice. Cells were incubated with 10 ug/ml PE-Labeled Mouse H-2K(b)&B2M&OVA (SIINFEKL) Tetramer.

Express System: HEK293
Product Tag: C-His-Avi
Amino Acid Range: His24-Pro297(H-2K(b)), Ile21-Met119(B2M) and SIINFEKL peptide

Catalog #MHC-MM453TP

Size

100UG

500UG

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Product Description	Recombinant PE-Labeled Mouse H-2K(b)&B2M&OVA (SIINFEKL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Mouse H-2K(b)&B2M&OVA (SIINFEKL) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains His24-Pro297 (H-2K(b)), Ile21-Met119 (B2M) and SIINFEKL peptide.
Product Background	Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its self-assembling nature.
Product Category	Recombinant Protein / Antibody discovery / MHC

Protein	H-2K(b)&B2M&OVA (SIINFEKL) Tetramer
Synonyms	H-2K; OVA; MHC; H2-K1;
MHC Form	Tetramer
Accession	P01901(H-2K(b))&P01887(B2M)&SIINFEKL
Species	Mouse
Biotinylated	no
Amino Acid Range	His24-Pro297(H-2K(b)), Ile21-Met119(B2M) and SIINFEKL peptide
Product Tag	C-His-Avi
Fluorophore	PE
Expression System	HEK293
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 300mM NaCl (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

PE-Labeled Mouse H-2K(b)&B2M&OVA (SIINFEKL) Tetramer can specifically bind to CD8+, OVA-specific T cells from OT-I TCR transgenic mice. Cells were incubated with 10 ug/ml PE-Labeled Mouse H-2K(b)&B2M&OVA (SIINFEKL) Tetramer.

Additional Information

Learn More: MHC Collection Learn More: Peptide-ready MHC Protocol: MHC Staining Case Study: Peptide-ready MHC for TCR Staining Poster: Engineering MHCs as Versatile Reagents Publication: Use of our Peptide-Ready MHCs in CAR-T Cell Research Product Brochure