• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Rabbit Coagulation factor XI, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-factor XI Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA (QC Test).
  • Amino Acid Range: Glu19-Pro624
Catalog #FXI-RM101
Price
Regular price $412.50
Regular price Sale price $412.50
/
Size
Avantor VWR Fisher Scientific

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Rabbit Coagulation factor XI Protein (pro form) (FXI-RM101) Summary

Product Description

 Recombinant Rabbit Coagulation factor XI Protein is expressed from HEK293 with His tag at the C-terminus. The protein needs to be activated by Thermolysin for an activated form.It contains Glu19-Pro624.

Product Background

 Coagulation factor (F)XI has been described as a component of the early phase of the contact pathway of blood coagulation, acting downstream of factor XII.In contrast to its mild hemostatic activities, FXI is known to play a significant role in thrombosis, as it is a demonstrated independent risk factor for deep vein thrombosis, ischemic stroke, and myocardial infarction. A better understanding of the varied and complex role of FXI in both thrombosis and hemostasis will help to allow better prediction of bleeding risk in FXI-deficient patients and also informing the development of targeted agents to inhibit the thrombotic activities of FXI while preserving hemostasis.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery/Others

Rabbit Coagulation factor XI Protein (pro form) (FXI-RM101) Specifications/Details

Protein
 Coagulation factor XI
Synonyms
 Coagulation factor XI; FXI; PTA; F11;
Accession
Species
 Rabbit
Biotinylated
 no
Amino Acid Range
 Glu19-Pro624
Molecular Weight
 The protein has a predicted MW of 69.61 kDa. Due to glycosylation, the protein migrates to 70-90 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Rabbit Coagulation factor XI, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-factor XI Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA (QC Test).
Product Tag
 C-His

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Rabbit Coagulation factor XI, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-factor XI Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA (QC Test). Immobilized Rabbit Coagulation factor XI, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-factor XI Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA (QC Test).
Rabbit Coagulation factor XI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Rabbit Coagulation factor XI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Rabbit Coagulation factor XI is greater than 95% as determined by SEC-HPLC. The purity of Rabbit Coagulation factor XI is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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