- Express System: HEK293
- Product Tag: No Tag
- Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
- Activity: Immobilized Rabbit IgG, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Fc gamma RI, His Tag with the EC50 of 4.7ng/ml determined by ELISA (QC Test). See testing image for detail.
- Amino Acid Range: Ser101-Lys323(T185A, N284S)
Product Description |
Recombinant Rabbit IgG Protein is expressed from HEK293 without tag.It contains Ser101-Lys323 (T185A, N284S). |
Product Background |
Immunoglobulin G (IgG) glycosylation can modulate antibody effector functions. Depending on the precise composition of the sugar moiety attached to individual IgG glycovariants either pro- or anti-inflammatory effector pathways can be initiated via differential binding to type I or type II Fc-receptors. Rabbits make high-affinity IgG antibodies, all of which bind with high affinity to Protein A from Staphylococcus aureus and Protein G from Group G Streptococcus. |
Product Category |
Recombinant Protein / Antibody discovery / Fc receptors |
Protein |
IgG |
Synonyms |
IgG; |
Accession |
|
Species |
Rabbit |
Biotinylated |
no |
Amino Acid Range |
Ser101-Lys323(T185A, N284S) |
Molecular Weight |
The protein has a predicted MW of 25.13 kDa. Due to glycosylation, the protein migrates to 30-38 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Rabbit IgG, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Fc gamma RI, His Tag with the EC50 of 4.7ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
No Tag |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 150mM Nacl, 10% Glycerol (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
More from Antibody Drug Discovery Proteins
Recently viewed