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Rat ADAM9 Protein (ADM-RM119) Summary
Product Description |
Recombinant Rat ADAM9 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala206-Asp697. |
Product Background |
A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS. |
Product Category |
Recombinant Protein / Antibody discovery / ADC targets |
Rat ADAM9 Protein (ADM-RM119) Specifications/Details
Protein |
ADAM9 |
Synonyms |
ADAM 9; Meltrin-gamma; Mdc9; Mltng; Adam9; Kiaa0021; AU020942; MDC9; mKIAA0021; CORD9; MCMP; MLTNG |
Accession |
|
Species |
Rat |
Biotinylated |
no |
Amino Acid Range |
Ala206-Asp697 |
Molecular Weight |
The protein has a predicted MW of 75.11 kDa. Due to glycosylation, the protein migrates to 65-95 kDa based on Bis-Tris PAGE result. |
Activity |
Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is > 2.0 pmol/min/ug. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 50mM Tris, 500mM NaCl, 0.005% Brij-35, 20% glycerol (pH 8.5). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Rat ADAM9 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Rat ADAM9 is greater than 90% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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